TABLE 2

Substrate kinetics

FedFasted
Rd Glucose (μmol/kg/min)
    Basal11.3 ± 0.67.6 ± 0.4*
    Clamp38.0 ± 2.818.8 ± 0.9*
    Delta26.7 ± 2.611.2 ± 1.0*
EGP (μmol/kg/min)
    Basal10.7 ± 0.66.8 ± 0.3*
    Clamp−1.0 ± 0.40.7 ± 0.4*
    Delta absolute−11.7 ± 0.6−6.07 ± 0.5*
    Delta %111.6 ± 5.990.0 ± 6.7*
CHO oxidation (μmol/kg/min)
    Basal9.7 ± 0.83.4 ± 0.6*
    Clamp20.8 ± 1.16.6 ± 0.8*
    Delta11.1 ± 0.93.4 ± 0.7*
NOGD (μmol/kg/min)
    Basal1.6 ± 0.54.2 ± 0.8*
    Clamp17.2 ± 2.212.6 ± 0.8*
    Delta15.6 ± 2.48.2 ± 1.1*
Lipid oxidation (μmol/kg/min)
    Basal1.2 ± 0.01.8 ± 0.2*
    Clamp0.3 ± 0.11.52 ± 0.1*
    Delta−0.8 ± 0.1−0.31 ± 0.1*
  • Values are mean ± SE.

  • *P < 0.05. EGP, endogenous glucose production; CHO, carbohydrate; NOGD, nonoxidative glucose disposal.