TABLE 1

Clinical and biochemical characteristics of the type 2 diabetic and control subjects studied

T2DM (n = 8)Control subjects (n = 10)
Age (years)63 ± 352 ± 6
BMI (kg/m2)28.9 ± 0.826.4 ± 0.8
Disease duration (years)17 ± 2
HbA1C (%)8.38 ± 0.295.44 ± 0.23
Fasting glucose (mmol/l)12.1 ± 1.04.8 ± 0.1
Fasting insulin (pmol/l)99 ± 1846 ± 8
Plasma creatinine (μmol/l)105 ± 1175 ± 2
Glomerular filtration rate (measured) (ml/m2 · min)85 ± 6
Glomerular filtration rate (calculated) (ml/m2 · min)86 ± 9117 ± 13
Albuminuria (g/day)1.9 ± 0.6<0.03
Total cholesterol (mmol/l)4.9 ± 0.34.9 ± 0.3
HDL cholesterol (mmol/l)1.2 ± 0.11.3 ± 0.1
Triglycerides (mmol/l)1.8 ± 0.41.1 ± 0.2
TNF-α (pg/ml)150 ± 5080 ± 14
IL-6 (pg/ml)68 ± 4910 ± 3
IL-8 (pg/ml)72 ± 1227 ± 5
IL-10 (pg/ml)0.37 ± 0.090.44 ± 0.11
hsCRP (mg(L)3.73 ± 1.480.73 ± 0.23
  • *P < 0.05.

  • P < 0.02 or less vs. control subjects. T2DM, type 2 diabetic subjects.