TABLE 2

Change in least squares means* of common IMT over EDIC years 1, 6, and 12 by treatment group

Change in least squaresMean IMT difference (mm ± SE)
EDIC periodIntensiveConventional(Intensive − Conventional)P
Years 1 to 60.016 ± 0.0100.036 ± 0.010−0.019 ± 0.005<0.0001
Years 6 to 120.057 ± 0.0050.051 ± 0.0050.005 ± 0.0060.379
Years 1 to 120.072 ± 0.0110.086 ± 0.010−0.014 ± 0.0070.048
  • *From a single general linear mixed model with effects for treatment group, age, sex, study cohort, IMT at year 1, IMT reader, image device, EDIC year 6 or 12, and group by EDIC year interactions. Changes from years 1 to 6, 6 to 12, and 1 to 12 were estimated by contrasts among the model coefficients.