TABLE 5

Multivariable models to predict regression to NGR in DPP participants

VariablesHR (95% CI)P
Weighted GRS (per risk allele)0.95 (0.93–0.98)<0.0001
Metformin (vs. placebo)1.26 (0.98–1.62)0.08
Lifestyle (vs. placebo)2.38 (1.89–2.99)<0.0001
Female (vs. male)0.81 (0.66–0.99)0.04
African American (vs. white)1.22 (0.95–1.58)0.12
Hispanic (vs. white)0.96 (0.74–1.24)0.76
Asian/Pacific Islander (vs. white)0.52 (0.31–0.84)0.009
American Indian (vs. white)1.16 (0.63–2.14)0.64
Age at randomization (per year)0.98 (0.97–0.99)<0.0001
Waist circumference (per cm)0.98 (0.98–0.99)<0.0001