TABLE 1

Subject characteristics

T1D− patientsT1D+ patientsControl subjects
Sex (male/female)6/26/26/2
Age (years)32.1 ± 2.226.9 ± 1.027.9 ± 5.4
BMI (kg/m2)23.5 ± 0.624.4 ± 2.823.8 ± 0.4
HbA1c (%)6.93 ± 0.206.35 ± 0.205.10 ± 0.10
Diabetes duration (years)10.6 ± 2.2*3.2 ± 0.7
ICA (positive/negative)3/52/6
GAD-65 (positive/negative)6/27/1
Insulin (IE/day)47 ± 3.5*31.9 ± 0.5
Meal insulin (IE) (study days)3.80 ± 0.84*2.6 ± 0.5
Stimulated C-peptide (pM)<33*456 ± 221
  • Data are mean ± SEM. Characteristics of type 1 diabetic patients without (−) and with (+) residual β-cell function and control subjects. GAD-65, glutamic acid decarboxylase-65; ICA, islet cell antibody.

  • *P < 0.05 vs. T1D+.