TABLE 2

Clinical study I: Pearson correlation coefficients of the changes in study variables before and after 16 weeks of treatment

Change in variableLeptinFree leptinLeptin antibodyLBPIL-6CRPsTNFR-IsTNFR-IIMCP1sICAM-1IL-10
BMI
r−0.08−0.17−0.110.110.200.00−0.04−0.020.220.10−0.18
P value0.5310.3720.8120.3950.1220.9910.7540.8660.1130.4320.424
Leptin
r0.440.990.000.02−0.170.00−0.070.02−0.16−0.02
P value0.012<0.00010.9750.90.160.9990.5830.850.2030.932
Free leptin
r0.22−0.17−0.13−0.22−0.040.180.16−0.050.29
P value0.6010.3630.4940.2360.8080.3250.40.7820.274
Leptin antibody
r0.310.09−0.250.140.150.18−0.07−0.13
P value0.4160.8270.5210.7280.6990.6410.8530.806
LBP
r0.140.440.250.18−0.080.26−0.13
P value0.2410.00020.0430.1320.5220.0310.503
IL-6
r0.300.210.250.070.200.22
P value0.0150.0810.0410.6190.1090.27
CRP
r0.430.470.050.490.26
P value0.0003<0.00010.723<0.00010.186
sTNFR-I
r0.620.090.400.50
P value<0.00010.5130.00070.008
sTNFR-II
r0.220.520.66
P value0.091<0.00010.0002
sICAM-1
r0.43
P value0.028
  • MCP, monocyte chemoattractant protein; sICAM, soluble intracellular adhesive molecule.