TABLE 1

Blood metabolic and inflammatory parameters

LeanObese before surgeryObese after surgery
6 females, 2 males11 females, 2 males
Age (years)29.5 ± 434.0 ± 10
BMI (kg/m2)20.9 ± 2.439.1 ± 1.9*28.1 ± 2.8*§
WC (cm)72.2 ± 9.2110.3 ± 9.9*89.7 ± 8.7*§
HC (cm)91.3 ± 7.3127.0 ± 5.2*105.0 ± 7.5*§
Glucose (mg/dL)80.6 ± 3.184.3 ± 6.177.9 ± 7.3
HbA1c (%)4.8 ± 0.25.2 ± 0.35.1 ± 0.3
Insulin (pmol/L)25.0 ± 10.368.7 ± 38.1*21.5 ± 10.4§
HOMA-IR0.7 ± 0.32.1 ± 1.2*0.6 ± 0.2§
Cholesterol (mg/dL)189 ± 28153 ± 24141 ± 16
HDL (mg/dL)74.5 ± 25.736.9 ± 5.8*52.6 ± 9.1*§
LDL (mg/dL)99.5 ± 22.497.6 ± 26.473.6 ± 16.1
Triglycerides (mg/dL)75.5 ± 38.994.1 ± 27.176.6 ± 19.9
CRP (mg/dL)0.13 ± 0.020.91 ± 0.70*0.17 ± 0.02§
ESR (mm/1 h)14 ± 1226 ± 16*16 ± 9§
Adiponectin (μg/mL)6.9 ± 1.72.7 ± 1.8*7.8 ± 1.6§
Leptin (ng/mL)21.4 ± 6.236.8 ± 12.0*17.0 ± 13.9§
TNF-α (pg/mL)5.8 ± 5.525.6 ± 10.3*12.4 ± 9.8§
IL-1β (pg/mL)2.0 ± 1.842.9 ± 26.7*13.6 ± 4.3*§
IL-6 (pg/mL)4.1 ± 4.226.3 ± 10.2*8.5 ± 6.4§
IL-10 (pg/mL)14.0 ± 10.115.6 ± 16.515.8 ± 5.5
  • CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; HC, hip circumference; HOMA-IR, homeostasis model assessment of insulin resistance; WC, waist circumference.

  • *P < 0.05 vs. lean.

  • §P < 0.05 vs. obese before surgery.