TABLE 1

Clinical characteristics of the subjects

Lean (9)Obese (9)Type 2 diabetes (8)
Sex (male/female)6/35/46/2
Age (years)23.8 ± 0.823.7 ± 0.853.8 ± 3.8b,e
Body weight (kg)66.4 ± 3.694.5 ± 3.4c102.4 ± 4.2c
BMI (kg/m2)22.5 ± 0.532.9 ± 0.5c35.4 ± 1.7c
Body fat (%)20.4 ± 2.831.1 ± 1.6a37.5 ± 2.9b
GDR (mg/min/kg FFM)9.3 ± 0.87.0 ± 0.6a5.3 ± 0.6c
Fasting glucose (mmol/L)4.67 ± 0.124.81 ± 0.13a7.51 ± 0.76b,d
Fasting insulin (mU/L)8.4 ± 1.213.2 ± 1.1a13.7 ± 2.9a
  • Data are mean ± SEM.

  • FFM, fat-free mass; GDR, glucose disposal rate.

  • aP < 0.05,

  • bP < 0.01,

  • cP < 0.001 vs. lean;

  • dP < 0.01,

  • eP < 0.001 vs. obese.