TABLE 4

Associations between genotypes of rs4783244 on CDH13 and HOMA-IR and the risk of diabetes

TraitSexrs4783244P value
G/GG/TT/T
Mean ± SD (n)
HOMA-IRMale1.67 ± 0.53 (494)1.65 ± 0.52 (468)1.54 ± 0.39 (175)0.033
HOMA-IRFemale1.69 ± 0.52 (793)1.69 ± 0.52 (803)1.70 ± 0.53 (175)0.700
OR (95% CI)
DMMale3.25 (1.15–9.19)3.50 (1.24–9.8)1
P = 0.026P = 0.018
DMFemale1.51 (0.6–2.22)0.98 (0.5–1.91)1
P = 0.674P = 0.960
  • HOMA-IR stratified by sex was averaged by genotypes of rs4783244. DM, diabetes mellitus.

  • P values were obtained from GLM with adjustments for age and smoking.

  • P values were obtained from logistic regression analysis with adjustments for age and smoking.