TABLE 1

Metabolic parameters after 12 weeks of HFD

GenotypeArntF/FArnt∆AdipoHif1aF/FHif1α∆Adipo
Fasting glucose (mg/dL)150 ± 21.7106 ± 21.5*172 ± 32.5131 ± 19.8*
Fed glucose (mg/dL)269 ± 28.1139 ± 27.9206 ± 23.5149 ± 30.4
Fasting serum insulin (ng/mL)3.6 ± 1.42.1 ± 0.8*2.6 ± 0.61.1 ± 0.2
HOMA index31.7 ± 8.613.8 ± 7.627.9 ± 10.48.4 ± 1.8
Fasted serum triglyceride (mg/dL)124 ± 42.178.4 ± 7.5*162 ± 38.899.4 ± 19.8
Fasted serum cholesterol (mg/dL)182 ± 37.6169 ± 43.6196 ± 45.8160 ± 24.1
Fasted serum FFA (mmol/L)1.88 ± 0.421.07 ± 0.39*1.63 ± 0.351.09 ± 0.30*
  • Data are means ± SD.

  • *P < 0.05.

  • P < 0.01 compared with controls.