TABLE 4

Summary of whole brain and voxel-wise analyses and results by group and variable

Significant effects of diagnosis or exposure
T1DM vs. NDC
 Whole brain
  GrayNone
  WhiteNone
 Voxel-wise
  GrayNone
  WhiteNone
Hyperglycemia
 Whole brain
  GrayHigher HbA1c → greater decrease over time
  WhiteNone
 Voxel-wise
  GrayNone
  WhiteNone
Severe hypoglycemia
 Whole brain
  GrayNone
  WhiteNone
 Voxel-wise
  GrayNone
  WhiteAny severe hypoglycemia → greater decrease in occipital/parietal region over time
Mild hypoglycemia
 Whole brain
  GrayNone
  WhiteNone
 Voxel-wise
  GrayNone
  WhiteNone