TABLE 2

Effects of the SNPs on diabetic retinopathy and nephropathy in stage 1 samples

ChromosomeSNPPositionMinor/major alleleDiabetic retinopathyDiabetic nephropathy
OR (95% CI)POR (95% CI)P
7rs381239829237994C,T0.970 (0.816–1.153)0.7281.087 (0.915–1.292)0.341
7rs381238929244759A,G0.839 (0.679–1.036)0.1030.960 (0.778–1.185)0.704
7rs226990329247409C,A1.202 (0.976–1.481)0.0841.026 (0.832–1.264)0.813
7rs381238829249198G,C1.190 (0.967–1.464)0.1001.055 (0.858–1.298)0.611
7rs1775694129250007G,A0.747 (0.598–0.933)0.0100.941 (0.755–1.174)0.593
7rs1198173729250335A,G1.064 (0.736–1.536)0.7430.834 (0.578–1.204)0.334
7rs3905929255470G,A0.774 (0.657–0.912)0.0020.959 (0.814–1.131)0.621
7rs3906529262601A,G0.973 (0.711–1.331)0.8621.180 (0.862–1.614)0.300
7rs1715765829274254C,G0.858 (0.719–1.024)0.0901.051 (0.881–1.254)0.577
7rs24595529276307C,T0.784 (0.668–0.921)0.0030.989 (0.843–1.161)0.896
7rs24596229290153A,G0.800 (0.681–0.939)0.0060.989 (0.842–1.161)0.893
7rs3909929293095A,G0.910 (0.762–1.085)0.2931.042 (0.874–1.243)0.646
7rs3910129294462A,G1.049 (0.846–1.301)0.6640.884 (0.712–1.096)0.261
9rs1114013986145409A,G1.018 (0.848–1.221)0.8541.010 (0.841–1.211)0.918
9rs487778886146950C,T1.029 (0.866–1.221)0.7501.044 (0.880–1.240)0.620
9rs784907586149610C,T0.972 (0.787–1.199)0.7870.971 (0.787–1.198)0.783
9rs188874686155392T,C0.815 (0.538–1.234)0.3340.928 (0.602–1.380)0.661
9rs1114015686163694G,C0.922 (0.717–1.186)0.5280.919 (0.714–1.183)0.511
9rs1086802586164176G,A0.833 (0.703–0.987)0.0340.905 (0.764–1.072)0.249
9rs1153557586165034T,C0.671 (0.439–1.025)0.0650.762 (0.501–1.160)0.205
9rs655973286168692C,T1.152 (0.948–1.399)0.1541.080 (0.889–1.311)0.440
9rs747028786172665C,G0.840 (0.687–1.027)0.0900.963 (0.788–1.177)0.712
9rs393490286177401A,G1.103 (0.938–1.298)0.2371.018 (0.865–1.197)0.835
9rs445139086179563T,C1.000 (0.848–1.180)0.9981.042 (0.883–1.229)0.628
9rs1179382186184504G,A1.116 (0.861–1.447)0.4070.915 (0.706–1.187)0.503
11rs37648952945945T,C0.994 (0.802–1.231)0.9540.897 (0.724–1.112)0.321
11rs25834422956166A,G1.021 (0.860–1.211)0.8120.993 (0.837–1.179)0.940
11rs47585762973880G,A0.956 (0.726–1.259)0.7510.912 (0.692–1.201)0.512
11rs110247582981782T,C1.180 (0.640–2.174)0.5961.590 (0.853–2.962)0.144
11rs47585043000179A,G0.963 (0.724–1.279)0.7940.901 (0.678–1.198)0.473
11rs47586213009640A,G1.008 (0.851–1.194)0.9250.990 (0.836–1.173)0.911
11rs123635753030104G,A1.007 (0.783–1.294)0.9581.104 (0.859–1.420)0.438
11rs124219223035070T,C1.024 (0.868–1.209)0.7780.996 (0.844–1.175)0.961
11rs20711013050137A,G1.042 (0.885–1.225)0.6240.939 (0.798–1.105)0.451
11rs5723733055361C,T1.061 (0.878–1.281)0.5411.032 (0.854–1.247)0.745
11rs4510413060725A,G1.046 (0.881–1.243)0.6051.010 (0.851–1.200)0.906
11rs71118573068106A,G1.069 (0.876–1.306)0.5111.044 (0.855–1.274)0.676
11rs65783183072442T,C1.009 (0.792–1.284)0.9450.981 (0.770–1.248)0.873
11rs22900003073838T,A1.019 (0.801–1.296)0.8780.969 (0.762–1.233)0.799
11rs4065983076285C,T1.016 (0.859–1.203)0.8501.002 (0.847–1.185)0.980
11rs108331733094505A,T1.033 (0.837–1.275)0.7600.950 (0.770–1.173)0.635
11rs20842393106659G,A0.983 (0.831–1.163)0.8450.958 (0.810–1.133)0.617
13rs914270110243017C,G0.995 (0.847–1.169)0.9540.955 (0.812–1.122)0.573
13rs2391776110243425C,T0.937 (0.735–1.194)0.5991.006 (0.790–1.281)0.963
13rs1041466110244322C,T1.264 (0.945–1.691)0.1150.782 (0.584–1.048)0.100
13rs11069790110244401A,G0.937 (0.784–1.121)0.4771.102 (0.921–1.317)0.288
13rs4462453110251328G,A1.246 (0.902–1.719)0.1820.869 (0.629–1.199)0.392
13rs1411766110252160T,C1.094 (0.828–1.445)0.5300.991 (0.750–1.310)0.951
13rs12184748110253930C,T1.001 (0.845–1.186)0.9901.028 (0.868–1.217)0.754
13rs2150481110256550G,C1.079 (0.917–1.269)0.3621.030 (0.876–1.212)0.717
13rs2391778110258553T,A1.048 (0.888–1.236)0.5821.037 (0.879–1.223)0.666
13rs1547241110273605G,C1.108 (0.824–1.490)0.4970.858 (0.637–1.155)0.311
13rs10161791110281789G,A0.938 (0.786–1.121)0.4831.106 (0.926–1.321)0.264
13rs9587939110284951A,C0.965 (0.810–1.150)0.6931.055 (0.885–1.257)0.549
13rs4773068110288967A,G0.924 (0.771–1.107)0.3901.160 (0.968–1.390)0.108
  • P values <0.05 are shown in boldface. ORs with 95% CIs were calculated for the minor allele.