TABLE 1

Quantification of calcium imaging of dispersed β-cells isolated from control and ABCA1−P/−P mice

VariableABCA1+/+nABCA1−P/−PnP
Basal [Ca2+]i ratio0.343 ± 0.004180.368 ± 0.006170.0002
Response to
 Glucose (10 mmol/L)
  Peak ratio1.324 ± 0.044101.258 ± 0.01790.197
  Area under the curve3.542 ± 0.212102.916 ± 0.13590.027
 Tolbutamide (100 μmol/L)
  Peak ratio1.313 ± 0.03651.183 ± 0.05540.078
  Area under the curve2.621 ± 0.12652.213 ± 0.09340.042
 KCl (30 mmol/L)
  Peak ratio1.528 ± 0.059101.400 ± 0.047100.105
  Area under the curve3.943 ± 0.136103.429 ± 0.162100.024
  • Data are presented as mean ± SE.