Table 1

Characteristics of the subjects

VariableHealthy subjectsPatients with type 1 diabetesPatients with type 2 diabetes
No. of subjects37626
Age (years)54.2 ± 1.261.3 ± 1.9*53.5 ± 2.1
Sex (M/F)10/272/414/12
Diabetes duration (years)15.3 ± 3.914.5 ± 2.3
BMI23.7 ± 0.622.9 ± 2.624.4 ± 0.7
Fasting blood glucose (mg/dL)96.5 ± 2.7152.2 ± 12.6176.4 ± 13.2
Serum HbA1c (%)5.3 ± 0.17.8 ± 0.49.1 ± 0.4
Serum total cholesterol (mg/dL)216.7 ± 5.3200.0 ± 16.3193.1 ± 9.2
Serum triglycerides (mg/dL)121.4 ± 10.6140.5 ± 34.2218.8 ± 44.1*
Serum HDL (mg/dL)59.5 ± 2.553.3 ± 8.941.8 ± 2.4*
Plasma total PS (μg/mL)22.9 ± 1.815.7 ± 2.1§18.7 ± 1.8§
Plasma-free PS (μg/mL)9.6 ± 0.85.9 ± 0.6*6.8 ± 0.4*
Plasma C4BP (μg/mL)5.4 ± 0.25.2 ± 0.56.2 ± 0.2
  • Data are n or mean ± SEM. Statistical analysis by Student t test. Levels of HbA1c were measured by high-performance liquid chromatography and total cholesterol, triglyceride, and HDL levels by automated enzymatic methods at the clinical laboratory of Mie University Hospital.

  • *P < 0.05, compared with healthy subjects.

  • P < 0.01, compared with healthy subjects.

  • §P = 0.06, compared with healthy subjects. F, female; M, male.