Table 1

Baseline characteristics and laboratory data of the study population

PatientPhenotype of LDMutationSexAge (years)BMI (kg/m2)Leptin (μg/L)HbA1c
(% [mmol/mol])TG (mmol/L)
1PartialLMNAF2327.45.36.4 (46)16.3
2PartialLMNAF3428.75.28.9 (74)2.4
3PartialLMNAF4827.49.86.6 (49)2.5
4GeneralizedNDM1617.4<0.488.4 (68)9.2
5PartialNDF41303.68.0 (64)7.9
6GeneralizedNDF3320.7<0.488.1 (65)37.1
7PartialPPARγM5533.56.76.0 (42)23.2
8PartialNDF3930.811.27.6 (60)15.6
9PartialPPARγF5327.25.67.0 (53)4.3
  • LMNA, lamin A/C; ND, not detected; PPARγ, peroxisome proliferator–activated receptor-γ. F, female; M, male.