Table 1

The effect of a favorable adiposity genetic score on measures of adiposity and cardiometabolic disease risk in the UK Biobank study

OutcomeEffect sizeLower CIUpper CIPN
Body fat percentage (%)0.1260.1040.1498E-28118,012
BMI (kg/m2)0.0460.0290.0632E-7119,688
Body fat mass (kg)0.1560.1230.1903E-18118,024
Body fat-free mass (kg)−0.030−0.053−0.0070.01118,221
Height (cm)0.006−0.0170.0280.6120,084
Type 2 diabetes (OR)0.9430.9240.9632E-84,003 vs. 113,203
Systolic blood pressure (mmHg)−0.255−0.334−0.1762E-10120,008
Diastolic blood pressure (mmHg)−0.096−0.143−0.0487E-5119,821
Hypertension (OR)0.9820.9740.9893E-665,584 vs. 53,377
Heart disease (OR)0.9670.9500.9841E-45,758 vs. 113,930
  • Effects are given per carrying additional adiposity-increasing weighted allele.