Table 1

Subject characteristics

LeanPresurgery obesePostsurgery obeseP value lean vs. preP value pre vs. postP value lean vs. post
Sex4 female7 female7 female
Age (years)48.5 ± 4.745.1 ± 3.645.3 ± 3.5NSNSNS
BMI (kg/m2)23.6 ± 0.742.1 ± 2.235.3 ± 1.8<0.001<0.001<0.001
Body fat (%)30.6 ± 1.646.4 ± 1.240.6 ± 1.3<0.001<0.01<0.01
Systolic blood pressure (mmHg)116.3 ± 2.4125.1 ± 3.9119.1 ± 4.6NSNSNS
Diastolic blood pressure (mmHg)67.5 ± 6.371.7 ± 2.075.1 ± 1.7NSNSNS
Triglycerides (mg/dL)75.5 ± 13.3121.9 ± 17.5107.7 ± 11.2NSNSNS
Cholesterol (mg/dL)173.3 ± 22.9181.4 ± 13.2151.5 ± 11.2NS<0.01NS
HDL (mg/dL)60.8 ± 5.045.0 ± 2.745.0 ± 2.5<0.05NS<0.05
LDL (mg/dL)97.3 ± 15.5112.1 ± 11.984.8 ± 10.5NS<0.01NS
Hemoglobin A1c, % (mmol/mol)5.5 ± 0.1 (36.5 ± 1.4)6.0 ± 0.2 (42.3 ± 1.7)5.7 ± 0.1 (39.1 ± 1.4)<0.05NSNS
FPG (mg/dL)84.9 ± 1.7104.2 ± 7.886.7 ± 3.1<0.05<0.05NS
FSI (μIU/mL)4.3 ± 0.518.2 ± 2.77.5 ± 1.0<0.001<0.01<0.05
M value (mg/kg/min)7.8 ± 0.52.4 ± 0.32.9 ± 0.4<0.001NS<0.001
M value (mg/kg FFM/min)11.2 ± 0.74.4 ± 0.64.9 ± 0.6<0.001NS<0.001
HOMA-IR1.1 ± 0.14.4 ± 0.81.6 ± 0.3<0.01<0.05NS
  • Data are means ± SEM. FFM, fat-free mass.