Table 3

Partial Spearman correlation coefficients of IGF-I, IGFBP-2, and IGFBP-3 concentrations and molar ratio of IGF-I to IGFBP-3 at gestational weeks 10–14 with subsequent fasting plasma biomarkers at gestational weeks 15–26 among case subjects with GDM and control subjects without GDM*

HOMA-IRGlucoseInsulinCRP
Case subjects
 IGF-I0.240.120.25−0.22
 IGFBP-2−0.34−0.25−0.33§−0.05
 IGFBP-3−0.12−0.02−0.13−0.14
 Molar ratio of IGF-I to IGFBP-30.360.130.37−0.21
Control subjects
 IGF-I0.170.0020.18−0.07
 IGFBP-2−0.27−0.02−0.28−0.11
 IGFBP-30.040.040.040.04
 Molar ratio of IGF-I to IGFBP-30.15−0.050.17−0.13
  • *P values were adjusted for age, gestational age at blood collection, family history of diabetes, and prepregnancy BMI.

  • P < 0.05.

  • P < 0.001.

  • §P < 0.01.