F-D(N = 80) | 2h-D(N = 42) | F-2h-D(N = 37) | P value | |
---|---|---|---|---|

Fasting glucagon (pmol/L) | 8.8 (7.3; 10.6) | 14.3 (11.8; 17.3)^{a} | 14.8 (12.9; 17)^{a} | <0.001 |

30-min glucagon (pmol/L) | 9.3 (8.0; 10.8) | 13.9 (12.1; 16.1)^{a} | 15.9 (13.8; 18.3)^{a} | <0.001 |

120-min glucagon (pmol/L) | 5.6 (4.8; 6.5) | 6.5 (5.4; 8.0) | 6.9 (5.7; 8.3) | 0.355 |

Glucagon suppression, 30 min (%)^{*} | −6.2 (−21.6; 7.3) | 2.3 (−10.7; 13.8) | −7.4 (−17.7; 2.1) | 0.613 |

Glucagon suppression, 30–120 min (%)^{ǂ} | 41.0 (33.4; 47.7) | 53.1 (47.1; 58.3)^{a} | 56.6 (51.5; 61.2)^{a} | 0.001 |

Glucagon suppression, 120 min (%)^{§} | 37.1 (28.7; 44.4) | 54.2 (46.3; 60.8)^{a} | 53.4 (47.7; 58.5)^{a} | <0.001 |

Data are geometric mean (95% CI), unless otherwise indicated. F-D, diabetes diagnosed by fasting glucose only; 2h-D, diabetes diagnosed by 2-h glucose only; F-2h-D, diabetes diagnosed by both fasting and 2-h glucose levels.

^{a}*P*< 0.05 vs. NGT.*Calculated as: (1 − [glucagon

_{30 min}/glucagon_{0 min}]) × 100.ǂCalculated as: (1 − [glucagon

_{120 min}/glucagon_{30 min}]) × 100.§Calculated as: (1 − [glucagon

_{120 min}/glucagon_{0 min}]) × 100.