Table 6

Final product formulation for PHPIs

IngredientQuantity
Active ingredient
 Human pancreatic isletsFirst infusion: ≥5.0 × 103 IEQ /kg recipient BW (total IEQ/infusion) Subsequent infusion: ≥4.0 × 103 IEQ /kg recipient BW (total IEQ/infusion)
Inactive ingredients
 CMRL 1066 transplant media (n = 12) containing HEPES without sodium bicarbonateq.s. to 200 mL per bag
 Albumin human, USP2.5%
  • q.s., sufficient quantity; USP, U.S. Pharmacopeia.