Table 2

Changes in glycemic traits associated with each additional copy of the SLC30A8 rs13266634 C allele by gestational weight gain

InadequateAdequateExcessiveP for interaction
β (SE)Pβ (SE)Pβ (SE)P
Fasting glucose (mmol/L)
 Age-adjusted−0.25 (0.16)0.12−0.10 (0.07)0.160.12 (0.06)0.040.003
 Multivariable-adjusted*−0.18 (0.16)0.25−0.04 (0.05)0.460.13 (0.05)0.010.002
 + Zinc intake−0.18 (0.15)0.25−0.04 (0.05)0.440.12 (0.05)0.010.002
2-h glucose (mmol/L)
 Age-adjusted−0.93 (0.33)0.01−0.05 (0.18)0.790.11 (0.13)0.410.005
 Multivariable-adjusted*−0.68 (0.31)0.03−0.03 (0.15)0.850.13 (0.12)0.260.003
 + Zinc intake−0.68 (0.31)0.03−0.04 (0.16)0.820.13 (0.12)0.270.003
HbA1c (%)
 Age-adjusted−0.29 (0.12)0.02−0.10 (0.06)0.110.08 (0.06)0.160.002
 Multivariable-adjusted*−0.23 (0.11)0.04−0.08 (0.05)0.080.06 (0.05)0.210.004
 + Zinc intake−0.23 (0.11)0.05−0.08 (0.05)0.080.05 (0.05)0.280.005
  • β-Coefficients (SE) represent changes in each glycemic trait per additional copy of the rs13266634 C allele.

  • *Results were adjusted for age, follow-up time, prepregnancy BMI, total energy intake, sitting time, postpartum weight change, and the previous value for the respective glucose trait (continuous variables for above variables) and family history of diabetes, current smoking, current alcohol drinking, leisure time physical activity, and GDM therapy (categorical variables for above variables).