Table 2

Mean values and adjusted differences (95% CI) in metabolic syndrome–related parameters for comparison of the three highest ox-LDL quartiles with the first quartile

Quartiles of ox-LDL, units/L
≤39.9>39.9 and ≤49.4>49.4 and ≤60.8>60.8
n = 997n = 997n = 996n = 997P for trend
Mean ox-LDL, units/L33.0644.7254.6974.64
BMI, kg/m224.9325.5826.4127.37
 Basic model0.000.230.611.03<0.001
(Reference)(−0.07, 0.53)(0.29, 0.93)(0.68, 1.39)
 Full model*0.00−0.02−0.04−0.200.02
(Reference)(−0.17, 0.14)(−0.20, 0.13)(−0.38, –0.02)
Waist circumference, cm84.7287.1590.2094.20
 Basic model0.000.862.123.91<0.001
(Reference)(0.04, 1.68)(1.25, 2.99)(2.94, 4.87)
 Full model*0.000.420.761.43<0.001
(Reference)(0.01, 0.82)(0.33, 1.19)(0.95, 1.91)
Triglycerides, mg/dL71.8782.6495.22123.97
 Basic model0.008.4117.4842.47<0.001
(Reference)(4.06, 12.76)(12.87, 22.08)(37.36, 47.59)
 Full model0.008.9916.4738.20<0.001
(Reference)(4.91, 13.07)(12.14, 20.80)(33.37, 43.03)
HDL-cholesterol, mg/dL52.1750.4648.7445.56
 Basic model0.00−1.08−1.78−3.75<0.001
(Reference)(−2.04, −0.13)(−2.80, −0.77)(−4.88, −2.63)
 Full model0.00−1.04−1.31−2.55<0.001
(Reference)(−1.94, −0.13)(−2.28, −0.35)(−3.62, −1.47)
Total cholesterol, mg/dL178.75191.46206.37226.16
 Basic model0.000.591.714.75<0.001
(Reference)(−0.51, 1.70)(0.54, 2.89)(3.44, 6.05)
 Full model0.000.761.985.10<0.001
(Reference)(−0.35, 1.86)(0.80, 3.15)(3.79, 6.41)
LDL-cholesterol, mg/dL112.05124.34138.44155.65
 Basic model*0.0011.6425.1841.83<0.001
(Reference)(9.48, 13.81)(22.99, 27.37)(39.59, 44.06)
 Full model*0.0011.6524.8440.93<0.001
(Reference)(9.49, 13.81)(22.65, 27.03)(38.67, 43.19)
Systolic blood pressure, mmHg112.80114.50117.16119.72
 Basic model0.000.401.722.57<0.001
(Reference)(−0.56, 1.36)(0.70, 2.74)(1.45, 3.70)
 Full model0.000.271.201.50<0.001
(Reference)(−0.64, 1.19)(0.23, 2.17)(0.41, 2.58)
Diastolic blood pressure, mmHg69.9571.2573.1575.09
 Basic model0.000.371.392.27<0.001
(Reference)(−0.40, 1.15)(0.57, 2.21)(1.36, 3.18)
 Full model0.000.220.811.080.001
(Reference)(−0.49, 0.93)(0.05, 1.57)(0.23, 1.92)
Fasting glucose, mg/dL87.9488.4790.1091.28
 Basic model0.00−0.420.220.250.06
(Reference)(−1.13, 0.29)(−0.52, 0.97)(−0.58, 1.08)
 Full model0.00−0.230.06−0.650.27
(Reference)(−0.84, 0.37)(−0.58, 0.71)(−1.37, 0.06)
Insulin, pmol/L5.265.395.997.15
 Basic model0.00−0.140.181.00<0.001
(Reference)(−0.44, 0.17)(−0.14, 0.50)(0.64, 1.35)
 Full model0.000.000.060.31<0.001
(Reference)(−0.12, 0.13)(−0.07, 0.19)(0.16, 0.46)
HOMA-IR, log−0.010.020.130.31
 Basic model0.00−0.030.010.12<0.001
(Reference)(−0.08, 0.02)(−0.04, 0.07)(0.06, 0.18)
 Full model*0.00−0.06−0.050.000.21
(Reference)(−0.10, −0.01)(−0.10, −0.01)(−0.06, 0.05)
HbA1c, %5.315.385.445.46
 Basic model0.000.040.070.070.007
(Reference)(0.01, 0.07)(0.04, 0.10)(0.03, 0.10)
 Full model0.000.050.070.060.04
(Reference)(0.01, 0.08)(0.04, 0.10)(0.02, 0.09)
  • Differences are estimated from linear regression models with adjustment for age, sex, smoking status, and LDL-cholesterol (basic model), and additionally for HOMA-IR (log), BMI, and waist circumference (full model). Unadjusted means appear in boldface type.

  • *The outcome variable in these regressions was excluded from the adjustment variables.

  • †Mean HbA1c values were 34.6, 35.2, 35.9, and 36.1 mmol/mol for first to fourth quartiles of ox-LDL, respectively. The differences expressed in mmol/mol were approximately 10 times the data in the table.