Table 1

Metabolic parameters in fed and fasted mice

NCNC-GRHFDHFD-GR
Plasma triglyceride (mg/dL)139.2 ± 9.4140.7 ± 8.1144.6 ± 5.4123.6 ± 9.2
Plasma total cholesterol (mg/dL)161.2 ± 7.7161.4 ± 3.5212.6 ± 2.1**210.2 ± 1.8**
Plasma FFA (mmol/L)0.85 ± 0.070.96 ± 0.070.93 ± 0.050.81 ± 0.05
Blood glucose (mg/dL)
 Fed126 ± 6124 ± 3152 ± 4**145 ± 4*
 Fasted77 ± 376 ± 3131 ± 9**94 ± 5##
Plasma insulin (ng/mL)
 Fed1.4 ± 0.21.0 ± 0.25.3 ± 0.5**3.6 ± 0.4**#
 Fasted0.2 ± 0.00.1 ± 0.02.2 ± 0.2**1.3 ± 0.2**##
HOMA-IR1.0 ± 0.10.6 ± 0.217.7 ± 1.6**8.0 ± 1.3**##
  • Data are mean ± SEM (n = 9/group). Shown are blood glucose and plasma insulin levels of mice fed (ad libitum) or fasted for 16 h. Triglyceride, total cholesterol, and FFA levels were measured in fasting plasma. *P < 0.05, **P < 0.01 vs. NC; #P < 0.05, ##P < 0.01 vs. HFD.