Table 1

Comparison of NPI grafts precultured for 48 h with or without MSCs

Cell composition (% of total)
ConditionInsulin content (μg/pancreas)βαPCNA and β positive
NPI alone27.43 ± 3.2215.43 ± 0.4412.38 ± 0.355.20 ± 1.80
NPI + MSC34.60 ± 0.75*13.02 ± 0.4411.60 ± 0.335.10 ± 2.20
  • Data are mean ± SEM of four independent experiments. NPIs were precultured for 48 h in the absence (NPI alone) or presence of 106 human bone marrow–derived MSCs (NPI + MSC).

  • *P < 0.05 (Student t test).