Table 1

Consistency of the direction of effects of 80 known index SNPs on T2D between the HCHS/SOL and previously reported studies

Results in the HCHS/SOLConsistent SNPs/total SNPs (%)Binomial test P
SNPs showed consistency of direction69/80 (86.3)8.67 × 10−12
SNPs showed P < 0.0527/80 (33.8)7.56 × 10−16
SNPs showed P < 6.25 × 10−4*10/80 (12.5)1.43 × 10−20
  • *Bonferroni corrected significance in the current analysis (0.05/80 SNPs).