Table 2

Islet characteristics in humans, dogs, and NOD mice

α-Cellsβ-Cellsδ-CellsPP cells
Human40%; core + periphery50%; core + periphery10%; core + peripheryCore + periphery; rare except in uncinate process of head
Dog11%; core + periphery78%; core > periphery<11%; core + periphery<4%; core + periphery; predominantly right limb/head lobe
Mouse15–20%; periphery60–80%; core<10%; periphery<1% periphery
  • Adapted with permission from Steiner et al. (30). Information generated from refs. 2931,34.