Table 2

Metabolic parameters during IGIV and OGTT in obese subjects before and after BPD and in healthy control subjects

Before BPDAfter BPDControl
ParameterIGIVP valueOGTTPO/BPD OGTTIGIVP valueOGTTIGIVP valueOGTTPO/C OGTTPBPD/C OGTT
SG (× 102 min–1)1.46 ± 0.29NS2.06 ± 0.27NS4.71 ± 0.60NS4.01 ± 0.363.12 ± 0.32NS3.85 ± 0.310.039NS
SI (× 104 min–1 pmol/L–1)0.91 ± 0.260.0100.27 ± 0.060.0012.70 ± 0.55NS2.41 ± 0.372.69 ± 0.220.0212.03 ± 0.200.001NS
AUCISR (nmoles)59.44 ± 20.180.009135.63 ± 28.300.00112.92 ± 3.400.03626.44 ± 7.2228.99 ± 2.540.00936.90 ± 3.420.001NS
Φs (× 109 min–1)26.83 ± 7.060.01054.58 ± 10.980.02312.95 ± 2.380.01018.65 ± 2.8111.65 ± 0.760.01417.77 ± 1.760.002NS
Φd (× 109)273.6 ± 99.8NS364.7 ± 130.3NS156.0 ± 46.4NS274.0 ± 37.5391.20 ± 61.4NS399.2 ± 105.3NSNS
Φ (× 109 min–1)29.86 ± 7.460.00958.85 ± 11.440.02314.70 ± 2.530.01420.52 ± 2.7216.96 ± 0.830.04027.67 ± 4.150.031NS
ClINS (L · min–1)1.99 ± 0.59NS1.23 ± 0.12NS2.24 ± 0.94NS1.46 ± 0.351.09 ± 0.100.0120.79 ± 0.070.030NS
  • Data are mean ± SE. The columns between IGIV and OGTT report the statistical significance of differences observed between the two ways of glucose administration. The other three columns report statistical significance between OGTT parameters in obese subjects before and after BPD (PO/BPD), between OGTT before BPD and control (PO/C), and between OGTT after BPD and control (PBPD/C).