Table 1

Plasma metabolites in WT and Plin5MKO mice fed an HFD

WTPlin5MKO
Glucose (mmol/L)10.5 ± 0.410.7 ± 0.2
Insulin (pmol/L)698 ± 110527 ± 88
Triglyceride (μmol/L)538 ± 45609 ± 85
NEFA (μmol/L)484 ± 83478 ± 50
Cholesterol (mmol/L)3.6 ± 0.74.0 ± 0.8
β-Hydroxybutyrate (μmol/L)566 ± 58452 ± 22
ALT (units/mL)1.88 ± 0.380.82 ± 0.20*
AST (units/mL)0.78 ± 0.250.31 ± 0.09
TNFα (pg/mL)7.2 ± 1.26.4 ± 1.3
  • Values are mean ± SEM. Glucose: WT n = 12, Plin5MKO n = 10; insulin: WT n = 11, Plin5MKO n = 10; triglyceride/TNFα: WT n = 6, Plin5MKO n = 6; NEFA/β-hydroxybutyrate: WT n = 6, Plin5MKO n = 5; cholesterol: WT n = 5, Plin5MKO n = 5; ALT/AST: WT n = 5, Plin5MKO n = 4.

  • *P < 0.05.