Allele | β (SE) for fetuin concentration | P | F statistic | |
---|---|---|---|---|

Individual SNPs | ||||

rs4917 | T→C | 16.9 (8.4) | 0.0446 | <0.0001 |

rs2070635 | G→A | −0.6 (5.1) | 0.9013 | |

rs2070633 | T→C | 23.7 (8.2) | 0.0040 | |

rs2248690 | T→A | 12.3 (4.3) | 0.0040 | |

rs4831 | G→C | 1.1 (8.6) | 0.9008 | |

Genetic scores^{*} | ||||

Weighted score | 52.4 (2.8) | <0.0001 | <0.0001 | |

Unweighted score | 53.0 (2.8) | <0.0001 | <0.0001 |

β for individual SNPs obtained from one linear regression model including all five SNPs simultaneously. β for genetic scores obtained from single univariate linear regression models. SNPs and genetic scores modeled per fetuin-A–increasing allele and fetuin-A expressed in µg/mL.

*Genetic scores were created as sum of fetuin-A–increasing alleles of rs4917, rs2070633, and rs2248690, divided by three. β of the three SNPs from linear regression have been used as weights for the weighted genetic score.