Table 1

Characteristics of TEDDY children (n = 448) investigated for CBC when negative or positive for one or several IAs

IA negative (n = 376)IA positive (n = 72)
Children, n (%)376 (84)72 (16)
Sex, n
 Girls18230
 Boys19442
Age at first CBC (months), median (min–max)91 (52–145)101.5 (59–139) n.s.
 Girls91 (53–144)103 (59–139)
 Boys94 (52–145)99 (59–137)
CBC measures per child, min–max1–61–9
Months of follow-up, min–max1–301–30
IAs, n
 1025
 2016
 3031
Change in IA statusNoneNone
HLA DR-DQ, n (%)
 DR3/4-DQ2/8151 (40.2)39 (54.1)
 DR4/4-DQ 8/887 (23.1)12 (16.7)
 DR4/8-DQ 8/440 (10.6)12 (16.7)
 DR3/3-DQ 2/291 (24.2)9 (12.5)
 DR4/1-DQ 8/54 (1.1)0
 DR4/13-DQ 8/62 (0.5)0
 HLA ineligible1 (0.3)0
  Total376 (100)72 (100)