Table 4

Association analyses of circulating PEDF with STDR in the HKWDR cohort

With STDRWithout STDROR (95% CI)P value
N7724,317
PEDF (µg/mL)*9.97 (8.40–12.20)9.33 (7.94–11.07)2.06 (1.52–2.78)<0.001
Age (years)63.05 ± 12.8165.83 ± 12.491.00 (0.99–1.01)0.842
Sex (male)53.959.30.84 (0.72–0.99)0.034
Duration of diabetes (years)*16.0 (9.0–23.0)9.0 (4.0–15.0)2.05 (1.81–2.33)<0.001
Hypertension (%)86.594.31.98 (1.41–2.78)<0.001
HbA1c (%)*7.7 (6.9–8.7)7.3 (6.6–8.1)2.55 (1.58–4.14)<0.001
  • Data are mean ± SD, median (interquartile range), or %, unless stated otherwise.

  • *Natural-log transformed before analysis.

  • †Adjusted for traditional risk factors.