Table 2

The top 10 up- and downregulated genes in mouse primary hepatocytes transduced with PGC-1α-Ad compared with GFP-Ad–treated control cells

Gene symbolGene nameFold change
Upregulated
 G6pcGlucose-6-phosphatase catalytic subunit388.9
 Nr0b2Nuclear receptor subfamily 0 group B member 2290.7
 Cyp24a1Cytochrome P450 family 24 subfamily A member 1179.0
 Slc16a5Solute carrier family 16 member 5133.2
 LdhbLactate dehydrogenase B135.9
 Cox7a1Cytochrome C oxidase subunit 7A179.3
 CidecCell death–inducing DFFA-like effector C108.9
 Upp1Uridine phosphorylase 168.1
 Usp2Ubiquitin-specific peptidase 246.0
 Hpdl4-Hydroxyphenylpyruvate dioxygenase like46.8
Downregulated
 Fbxo5F-box protein 5−14.3
 E2f7E2F transcription factor 7−12.6
 Fignl1Fidgetin like 1−11.5
 Uhrf1Ubiquitin like with PHD and ring finger domains 1−10.8
 Ccne2Cyclin E2−10.1
 4632417K18RikRIKEN cDNA 4632417K18 gene−8.9
 Cdc2aCyclin D1−7.3
 CcnfCyclin F−7.3
 Shcbp1SHC binding and spindle associated 1−7.2
 AurkaAurora kinase A−6.9
  • Full data available at GEO with the accession number GSE114485.