Table 1

Effects of intensive, compared with conventional, glycemic therapy of type 2 diabetes: meta-analysis of 12 randomized controlled trials (20)

Effect (no. of randomized controlled trials)Relative risk95% CI (P)No. of patients
All-cause mortality (12)1.020.91–1.13 (0.74)28,359
Cardiovascular mortality (12)1.110.92–1.35 (0.27)28,359
Microvascular complications (3)0.880.79–0.97 (0.01)25,600
Severe hypoglycemia (9)2.391.71–3.34 (0.001)27,844