Table 4

Fatty acid composition in CE and SAT before and after 7 weeks of overeating PUFA or SFA

PUFA (n = 18)SFA (n = 19)Mean difference in change (95% CI)P value
BaselineMean changeBaselineMean change
CE
 14:00.61 ± 0.18−0.04 ± 0.160.62 ± 0.13−0.07 ± 0.090.03 (−0.06 to 0.12)0.5
 15:00.28 ± 0.06−0.03 ± 0.040.31 ± 0.07−0.06 ± 0.050.03 (−0.004 to 0.06)0.09
 16:010.6 ± 0.55−0.92 ± 0.5810.6 ± 0.570.3 ± 0.59−1.2 (−1.61 to −0.83)0.0001
 16:11.9 ± 0.45−0.52 ± 0.362.0 ± 0.620.03 ± 0.46−0.55 (−0.83 to −0.27)0.0003
 18:00.84 ± 0.17−0.11 ± 0.120.74 ± 0.13−0.06 ± 0.12−0.05 (−0.13 to 0.03)0.19
 18:121.8 ± 1.96−3.9 ± 1.1221.6 ± 1.83−0.02 ± 1.23−3.9 (−4.7 to −3.13)0.0001
 18:2 n-652.5 (51.63–55.08)6.4 ± 2.1253.3 (51.32–55.66)0.59 ± 2.295.8 (4.34–7.29)0.0001
 18:3 n-60.73 ± 0.280.06 ± 0.250.71 ± 0.260.07 ± 0.28−0.009 (−0.19 to 0.17)0.92
 18:3 n-30.84 ± 0.19−0.2 ± 0.140.97 ± 0.2−0.12 ± 0.17−0.07 (−0.17 to 0.03)0.17
 20:3 n-60.59 ± 0.110.03 ± 0.080.66 ± 0.170.02 ± 0.120.007 (−0.06 to 0.07)0.84
 20:4 n-66.3 ± 1.06−0.02 ± 0.756.01 ± 1.38−0.67 ± 0.60.64 (0.19–1.1)0.007
 20:5 n-31.3 ± 0.54−0.56 ± 0.561.1 ± 0.440.03 ± 0.6−0.6 (−0.98 to −0.21)0.004
 22:6 n-30.74 ± 0.21−0.16 ± 0.130.74 ± 0.19−0.05 ± 0.2−0.11 (−0.22 to 0.008)0.07
 SCD-10.18 ± 0.04−0.04 ± 0.030.19 ± 0.06−0.002 ± 0.04−0.03 (−0.06 to −0.009)0.008
SAT
 14:04.0 ± 0.70−0.3 ± 0.374.0 ± 0.78−0.16 ± 0.23−0.14 (−0.35 to 0.07)0.18
 15:00.35 ± 0.08−0.02 ± 0.020.35 ± 0.07−0.02 ± 0.02−0.006 (−0.02 to 0.008)0.42
 16:021.7 ± 1.55−1.1 ± 0.6621.7 ± 1.661.2 ± 1.18−2.3 (−2.9 to −1.6)0.0001
 16:14.3 ± 1.05−0.02 ± 0.414.4 ± 0.580.46 ± 0.52−0.49 (−0.81 to −0.17)0.004
 17:00.32 ± 0.08−0.03 ± 0.050.31 ± 0.05−0.03 ± 0.020 (0.03 to −0.03)1.0
 18:05.0 ± 0.96−0.35 ± 0.494.9 ± 0.81−0.44 ± 0.50.1 (−0.24 to 0.43)0.56
 18:150.2 ± 2.41−0.63 ± 0.8350.4 ± 2.14−0.88 ± 1.00.26 (−0.34 to 0.88)0.41
 18:2 n-611.6 (11.15–13.14)2.4 ± 1.0511.2 (10.15–12.78)−0.11 ± 0.282.5 (1.97–3.04)0.0001
 18:3 n-60.1 (0.09–0.11)0.009 ± 0.050.1 (0.09–0.16)0.004 ± 0.030.006 (−0.02 to 0.03)0.69
 18:3 n-31.1 ± 0.180.02 ± 0.081.2 ± 0.210.008 ± 0.090.009 (−0.05 to 0.06)0.75
 20:3 n-60.13 ± 0.020.002 ± 0.0090.13 ± 0.04−0.005 ± 0.0090.007 (0.001–0.01)0.018
 20:4 n-60.26 ± 0.060.01 ± 0.020.24 ± 0.070.009 ± 0.030.0006 (−0.02 to 0.02)0.95
 20:5 n-30.14 ± 0.04−0.007 ± 0.020.12 ± 0.030.0006 ± 0.02−0.007 (−0.02 to 0.006)0.27
 22:5 n-30.17 ± 0.04−0.008 ± 0.010.16 ± 0.04−0.01 ± 0.020.004 (−0.006 to 0.02)0.41
 22:6 n-30.15 ± 0.07−0.01 ± 0.020.16 ± 0.07−0.004 ± 0.03−0.007 (−0.03 to 0.01)0.41
 SCD-10.2 ± 0.050.009 ± 0.020.2 ± 0.030.009 ± 0.030.0005 (−0.02 to 0.02)0.96
  • Data are means ± SD or median (IQR) and 95% CI. For nonnormal variables, P values are obtained from nonparametric analyses. Fatty acids are reported as a percentage of all fatty acids assessed by gas chromatography. CE, cholesterol ester.