Table 5

Comparison of absolute gene expression difference before and after 7 weeks of overeating PUFA and SFA

Gene nameSymbolPUFA changeSFA changeFootnote
Carbonic anhydrase III, muscle specificCA31.551.02a,b,c
α-Kinase 3ALPK31.200.86a,b,c
Insulin-like growth factor 1IGF11.220.99a,b,c
Phosphodiesterase 8BPDE8B1.391.02a,b,c
Storkhead box 1STOX11.220.89a,b,c
MOCO sulphurase COOH-terminal domain containing 1MOSC11.171.00a,b,c
Heat-shock 70-kDa protein 12AHSPA12A1.521.17a,b,c
Glycerophosphodiester phosphodiesterase domain containing 5GDPD51.370.94a,b,c
Odz, odd Oz/ten-m homolog 4ODZ41.801.16a,c
Pleckstrin homology domain containing, family H member 2PLEKHH20.821.04a,c
Chloride intracellular channel 1CLIC10.871.03a,c
Connective tissue growth factorCTGF0.811.15a,c
Transmembrane protein 120BTMEM120B1.461.12c
Quinoid dihydropteridine reductaseQDPR1.251.05c
Aldehyde dehydrogenase 9 family, member A1ALDH9A11.321.08c
Transmembrane protein 120ATMEM120A1.100.94c
FAT tumor suppressor homolog 1FAT11.271.08c
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1PFKFB11.211.00c
Aldehyde dehydrogenase 1 family, member A1ALDH1A10.801.09c
  • Absolute expression difference after vs. before intervention groups is significant with aFDR 25% or bFDR 0%. cAbsolute expression differences after vs. before intervention was adjusted for differences in weight gain between individuals, followed by comparison between intervention groups at significance FDR 25%. For genes significant in this group only, weight change–adjusted differences in expression levels after vs. before intervention are shown.