Table 5

Sensitivity analysis by adjusting for macrosomia in a previous pregnancy, only in multiparous women (N = 172*; 30 with macrosomia vs. 142 without macrosomia)

OR95% CIP
sAF (for 1-AU increase)4.881.10–21.670.04
Weeks of amenorrhea at sAF measurement0.940.88–1.020.13
Age of mother1.050.94–1.160.41
SBP (mmHg)1.020.97–1.060.47
DBP (mmHg)0.990.94–1.040.72
BMI before pregnancy0.960.89–1.040.30
Type of diabetes
 Late GDMReference0.24
 Early GDM1.250.40–3.91
 Pregestational3.570.80–15.98
Family history of diabetes
 NoReference0.07
 Yes0.370.13–1.10
Parity
 1Reference0.63
 ≥21.280.47–3.47
Sex of newborn
 BoyReference0.54
 Girl1.360.51–3.64
Weeks of gestation at delivery1.200.85–1.670.30
Previous history of macrosomia
 NoReference
 Yes3.381.16–9.820.02
  • *Eleven women with missing data for at least one potential confounder among the 183 women with parity ≥1 were not included in the multivariate analysis.