Table 1

Baseline characteristics and outcomes of matched groups

No DM history (n = 12,318)DM history (n = 6,572)
VariableHG+
(n = 6,159)HG−
(n = 6,159)P valueHG+
(n = 3,286)HG−
(n = 3,286)P value
Age, mean ± SD, years71.5 ± 13.071.3 ± 13.20.39672.4 ± 10.372.9 ± 10.30.097
Male sex, %51.852.60.38757.056.90.980
Admission NIHSS, median (IQR)11 (6–17)11 (6–17)0.93710 (6–16)10 (6–16)0.193
Hypertension, %67.968.50.48685.085.50.531
Hyperlipidemia, %26.526.40.93548.350.00.175
Current smoking, %14.815.30.42113.013.10.826
Atrial fibrillation, %21.421.70.66122.322.00.744
Congestive heart failure, %8.38.30.97413.213.40.856
History of previous stroke, %9.99.60.58515.715.90.787
Prestroke disability (mRS >1), %12.311.80.42317.418.20.439
Statin pretreatment, %24.824.80.98347.046.80.863
Antiplatelet pretreatment, %34.634.40.86552.953.10.902
Anticoagulant pretreatment, %3.84.00.5785.24.80.461
Admission SBP baseline, mean ± SD, mmHg153.2 ± 24.3152.8 ± 23.70.364157.2 ± 24.2156.3 ± 24.10.115
Admission DBP, mean ± SD, mmHg83.0 ± 14.983.1 ± 14.80.85382.9 ± 14.882.4 ± 14.50.212
Admission plasma glucose, mean ± SD, mg/dL180.5 ± 40.4107.9 ± 17.3<0.001211.7 ± 62.1111.9 ± 19.5<0.001
Onset-to-treatment time, mean ± SD, min163.7 ± 65.0163.3 ± 65.80.750165.6 ± 64.1166.1 ± 64.80.735
SICH, %, SITS-MOST definition1.71.80.5632.22.70.224
SICH, %, ECASS II definition5.04.60.3076.95.80.084
Any PH, %5.14.60.1766.46.10.551
FFO, %40.644.2<0.00134.139.3<0.001
FI, %53.357.9<0.00148.252.5<0.001
Mortality at 3 months, %19.216.0<0.00123.719.9<0.001
3-month mRS, median (IQR)2 (1–4)2 (1–4)<0.0013 (1–5)2 (1–5)<0.001
  • DBP, diastolic blood pressure; PH, parenchymal hemorrhage; SBP, systolic blood pressure.