Table 4

Analysis of the top 18 T2DM-associated MVPs in nonblood tissues

CpG identifierChrGeneBlood, T2DM-CONLiver, T2DM-CONFatMuscle
T2DMCONT2DM-CONT2DM-CON PT2DM-CON, consistentT2DMCONT2DM-CONT2DM-CON PT2DM-CON, consistent
ORPT2DM-CONPConsistent
cg196930311TXNIP0.522.7E-21−0.0410.65True0.5010.4990.0020.71False0.5940.634-0.0400.02True
cg0650016121ABCG11.656.4E-140.0350.64True0.4770.4390.0380.02True0.3600.3490.0110.75True
cg144761011PHGDH0.672.8E-100.0800.14False0.5650.5610.0040.86False0.4830.484−0.0010.85True
cg1402017617SLC9A3R11.633.3E-100.0650.26True0.6780.686−0.0080.36False0.7410.748−0.0070.52False
cg1102468217SREBF11.566.0E-100.0810.24True0.6460.6400.0070.58True0.4060.3910.0160.96True
cg0639716122SYNGR11.514.5E-09−0.1450.07False0.5010.516−0.0150.09False0.5620.566−0.0050.78False
cg0057495811CPT1A0.695.2E-090.0590.42FALSE0.0910.096−0.0050.22True0.0970.103−0.0060.33True
cg0623542911NDUFV11.495.5E-09−0.0370.60False0.7930.7930.0010.43True0.7640.765−0.0010.82False
cg0577842417AKAP11.697.4E-090.0190.75True0.5830.594−0.0110.36False0.6440.648−0.0050.64False
cg1137614711SLC43A10.681.3E-080.0760.15False0.3010.305−0.0050.54True0.2820.285−0.0030.64True
cg048163117C7orf501.511.7E-080.0260.63True0.8530.861−0.0080.81False0.8790.885−0.0060.35False
cg0271160819SLC1A50.694.5E-080.0180.72False0.2450.256−0.0110.06True0.3560.376−0.0200.06True
cg08309687210.684.5E-080.0170.85False0.6340.653−0.0190.12True0.4460.4450.0010.85False
cg1351404271.424.5E-080.1300.09True0.7100.7060.0030.71True0.7320.7240.0070.55True
cg0899406010PFKFB30.655.2E-08−0.0950.17True0.1700.175−0.0050.86True0.1540.1430.0110.55False
cg016767957POR1.566.5E-08−0.0900.47False0.8510.852−0.0010.86False0.8900.892−0.0020.85False
cg251303811SLC9A11.496.7E-08−0.0690.14False0.6210.6100.0110.19True0.7640.776−0.0110.40False
cg1118322715MAN2A21.497.0E-08−0.1050.19False0.9450.946−0.0010.63False0.9060.910−0.0040.40False
  • Data are mean β unless otherwise indicated. CON, control subjects.