Table 4

Analysis of the top 18 T2DM-associated MVPs in nonblood tissues

CpG identifier	Chr	Gene	Blood, T2DM-CON		Liver, T2DM-CON			Fat					Muscle
			Blood, T2DM-CON		Liver, T2DM-CON			T2DM	CON	T2DM-CON	T2DM-CON P	T2DM-CON, consistent	T2DM	CON	T2DM-CON	T2DM-CON P	T2DM-CON, consistent
			OR	P	T2DM-CON	P	Consistent	T2DM	CON	T2DM-CON	T2DM-CON P	T2DM-CON, consistent	T2DM	CON	T2DM-CON	T2DM-CON P	T2DM-CON, consistent
cg19693031	1	TXNIP	0.52	2.7E-21	−0.041	0.65	True	0.501	0.499	0.002	0.71	False	0.594	0.634	-0.040	0.02	True
cg06500161	21	ABCG1	1.65	6.4E-14	0.035	0.64	True	0.477	0.439	0.038	0.02	True	0.360	0.349	0.011	0.75	True
cg14476101	1	PHGDH	0.67	2.8E-10	0.080	0.14	False	0.565	0.561	0.004	0.86	False	0.483	0.484	−0.001	0.85	True
cg14020176	17	SLC9A3R1	1.63	3.3E-10	0.065	0.26	True	0.678	0.686	−0.008	0.36	False	0.741	0.748	−0.007	0.52	False
cg11024682	17	SREBF1	1.56	6.0E-10	0.081	0.24	True	0.646	0.640	0.007	0.58	True	0.406	0.391	0.016	0.96	True
cg06397161	22	SYNGR1	1.51	4.5E-09	−0.145	0.07	False	0.501	0.516	−0.015	0.09	False	0.562	0.566	−0.005	0.78	False
cg00574958	11	CPT1A	0.69	5.2E-09	0.059	0.42	FALSE	0.091	0.096	−0.005	0.22	True	0.097	0.103	−0.006	0.33	True
cg06235429	11	NDUFV1	1.49	5.5E-09	−0.037	0.60	False	0.793	0.793	0.001	0.43	True	0.764	0.765	−0.001	0.82	False
cg05778424	17	AKAP1	1.69	7.4E-09	0.019	0.75	True	0.583	0.594	−0.011	0.36	False	0.644	0.648	−0.005	0.64	False
cg11376147	11	SLC43A1	0.68	1.3E-08	0.076	0.15	False	0.301	0.305	−0.005	0.54	True	0.282	0.285	−0.003	0.64	True
cg04816311	7	C7orf50	1.51	1.7E-08	0.026	0.63	True	0.853	0.861	−0.008	0.81	False	0.879	0.885	−0.006	0.35	False
cg02711608	19	SLC1A5	0.69	4.5E-08	0.018	0.72	False	0.245	0.256	−0.011	0.06	True	0.356	0.376	−0.020	0.06	True
cg08309687	21		0.68	4.5E-08	0.017	0.85	False	0.634	0.653	−0.019	0.12	True	0.446	0.445	0.001	0.85	False
cg13514042	7		1.42	4.5E-08	0.130	0.09	True	0.710	0.706	0.003	0.71	True	0.732	0.724	0.007	0.55	True
cg08994060	10	PFKFB3	0.65	5.2E-08	−0.095	0.17	True	0.170	0.175	−0.005	0.86	True	0.154	0.143	0.011	0.55	False
cg01676795	7	POR	1.56	6.5E-08	−0.090	0.47	False	0.851	0.852	−0.001	0.86	False	0.890	0.892	−0.002	0.85	False
cg25130381	1	SLC9A1	1.49	6.7E-08	−0.069	0.14	False	0.621	0.610	0.011	0.19	True	0.764	0.776	−0.011	0.40	False
cg11183227	15	MAN2A2	1.49	7.0E-08	−0.105	0.19	False	0.945	0.946	−0.001	0.63	False	0.906	0.910	−0.004	0.40	False

Data are mean β unless otherwise indicated. CON, control subjects.