Table 1

Clamp parameters

Rest dayExercise day
Pre clampEnd clampPre clampEnd clamp
Glucose infusion rate (µmol · min−1 · kg−1)30.3 ± 3.424.2 ± 2.7*
Hepatic glucose production (µmol · min−1 · kg−1)17.5 ± 0.85.1 ± 2.2¤¤¤17.7 ± 0.74.2 ± 1.9¤¤¤
Rd (µmol · min−1 · kg−1)17.5 ± 0.836.6 ± 3.2¤¤¤17.7 ± 0.730.0 ± 3.3¤¤**
Glucose oxidation (µmol · min−1 · kg−1)5.1 ± 1.713.5 ± 2.3¤¤4.8 ± 1.813.4 ± 2.3¤¤
NOGD (µmol · min−1 · kg−1)12.5 ± 1.923.1 ± 3.4¤¤12.8 ± 1.616.6 ± 2.7¤¤(*)
RER0.75 ± 0.020.85 ± 0.02¤¤¤0.74 ± 0.020.83 ± 0.02¤¤¤
Arterial plasma glucose (mmol · L−1)5.2 ± 0.15.1 ± 0.15.0 ± 0.15.0 ± 0.1
Arterial plasma insulin (µIU · mL−1)8 ± 1128 ± 9¤¤¤8 ± 2123 ± 12¤¤¤
  • Data are means ± SEM. N = 8, except for hepatic glucose production, Rd, glucose oxidation, and NOGD (n = 7). End clamp, mean last 20 min of EHC (hepatic glucose production, Rd, glucose oxidation, and NOGD) or last 40 min of EHC (glucose infusion rate and arterial plasma glucose, insulin, and FAs); Pre clamp, mean of blood samples taken 30 min and 0 min before EHC; RER, respiratory exchange ratio.

  • * P < 0.05,

  • ** P < 0.01 vs. rest day;

  • ¤¤ P < 0.01,

  • ¤¤¤ P < 0.001 vs. pre clamp;

  • ¤¤P < 0.01,

  • ¤¤¤P < 0.001 main effect of clamp;

  • (*) P = 0.12 for the interaction day × insulin (power = 0.26).