Table 4

Correlations of FA, hsTNT, and proBNP with neurophysiological data, ultrasound, ECG, and blood pressure measurements

hsTNTproBNPFA
Control subjectsAll T2DControl subjectsAll T2DControl subjectsAll T2D
Sural NCVs (m/s)r = 0.36, P = 0.347nsr = −0.65, P < 0.001***r = −0.31, P = 0.416nsr = −0.30, P = 0.452nsr = −0.67, P = 0.049*r = 0.40, P = 0.033*
Sural SNAPs (µV)r = 0.49, P = 0.176nsr = −0.07, P = 0.365nsr = 0.46, P = 0.216nsr = −0.14, P = 0.174nsr = −0.22, P = 0.577nsr = 0.22, P = 0.199ns
Tibial NCVs (m/s)r = 0.49, P = 0.180nsr = −0.44, P = 0.002**r = −0.15, P = 0.708nsr = 0.09, P = 0.536nsr = 0.40, P = 0.280nsr = 0.37, P = 0.011*
Tibial CMAPs (mV)r = 0.12, P = 0.764nsr = −0.53, P < 0.001***r = −0.07, P = 0.860nsr = −0.01, P = 0.954nsr = −0.21, P = 0.580nsr = 0.57, P < 0.001***
Tibial DMLs (ms)r = 0.27, P = 0.480nsr = 0.50, P < 0.001***r = −0.32, P = 0.405nsr = 0.02, P = 0.919nsr = 0.25, P = 0.516nsr = −0.32, P = 0.029*
Peroneal NCVs (m/s)r = 0.38, P = 0.311nsr = −0.42, P = 0.003**r = 0.10, P = 0.791nsr = −0.03, P = 0.832nsr = 0.18, P = 0.651nsr = 0.48, P < 0.001***
Peroneal CMAPs (mV)r = −0.47, P = 0.201nsr = −0.29, P = 0.044*r = 0.25, P = 0.513nsr = −0.13, P = 0.382nsr = 0.24, P = 0.530nsr = 0.65, P < 0.001***
Peroneal DMLs (ms)r = 0.39, P = 0.306nsr = 0.21, P = 0.142nsr = −0.32, P = 0.406nsr = −0.10, P = 0.492nsr = −0.33, P = 0.379nsr = −0.37, P = 0.009**
24-h systolic MAP (mmHg)r = 0.45, P = 0.319nsr = 0.19, P = 0.304nsr = 0.21, P = 0.662nsr = 0.22, P = 0.217nsr = <0.01, P > 0.999nsr = 0.04, P = 0.843ns
24-h diastolic MAP (mmHg)r = 0.17, P = 0.748nsr = −0.10, P = 0.570nsr = 0.64, P = 0.139nsr = −0.14, P = 0.454nsr = 0.107, P = 0.840nsr = −0.10, P = 0.578ns
24-h MAP (mmHg)r = 0.09, P = 0.867nsr = 0.05, P = 0.789nsr = 0.20, P = 0.714nsr < 0.01, P = 0.995nsr = 0.14, P = 0.803nsr = −0.04, P = 0.950ns
24-h mean pulse frequency (bpm)r = −0.04, P = 0.943nsr = −0.40, P = 0.022*r = 0.21, P = 0.662nsr = −0.58, P < 0.001***r = 0.61, P = 0.09nsr = −0.10, P = 0.585ns
PWV (m/s)r = −0.14, P = 0.726nsr = 0.46, P = 0.001**r = 0.13, P = 0.735nsr = 0.38, P = 0.007**r = 0.46, P = 0.214nsr = −0.31, P = 0.033**
ABI leftr = −0.24, P = 0.510nsr = −0.07, P = 0.649nsr = 0.59, P = 0.08nsr = −0.20, P = 0.160nsr = 0.11, P = 0.766nsr = 0.07, P = 0.654ns
ABI rightr = −0.29, P = 0.417nsr = −0.18, P = 0.219nsr = 0.45, P = 0.195nsr = −0.28, P = 0.046*r = 0.32, P = 0.369nsr = 0.08, P = 0.572ns
HRV test pulse frequency
 In lying position (bpm)r = 0.16, P = 0.697nsr = −0.08, P = 0.599nsr = 0.03, P = 0.957nsr = 0.31, P = 0.029*r = 0.63, P = 0.075nsr = −0.01, P = 0.933ns
 In standing position (bpm)r = 0.07, P = 0.879nsr = −0.15, P = 0.288nsr = −0.36, P = 0.339nsr = 0.45, P = 0.001**r = 0.33, P = 0.385nsr = 0.06, P = 0.666ns
HRV test E/I quotientr = 0.44, P = 0.242nsr = −0.21, P = 0.148nsr = 0.63, P = 0.076nsr = −0.23, P = 0.101nsr = −0.288, P = 0.459nsr = 0.15, P = 0.304ns
HRV test 30/15 quotientr = −0.62, P = 0.087nsr = 0.08, P = 0.602nsr = 0.32, P = 0.388nsr = −0.24, P = 0.101nsr = −0.16, P = 0.684nsr = −0.17, P = 0.244ns
IMT left carotid arteryr = 0.26, P = 0.477nsr = 0.11, P = 0.454nsr = 0.22, P = 0.541nsr = 0.11, P = 0.454nsr = −0.20, P = 0.580nsr = 0.01, P = 0.676ns
IMT right carotid arteryr = 0.33, P = 0.359nsr = 0.19, P = 0.194nsr = −0.30, P = 0.408nsr = 0.24, P = 0.091nsr = −0.09, P = 0.803nsr = −0.16, P = 0.403ns
Abdominal aorta diameter (mm)r = −0.54, P = 0.11nsr = −0.14, P = 0.350nsr = −0.11, P = 0.768nsr = 0.05, P = 0.726nsr = −0.05, P = 0.883nsr = −0.10, P = 0.607ns
  • All values are displayed as mean ± SD. DML, distal motor latencies; E/I quotient, quotient of the longest RR interval under expiration and the shortest RR interval under inspiration in the HRV test; HRV, heart rate variability; MAP, mean arterial pressure; n.a., not applicable; 30/15 quotient, quotient of the longest RR interval between beat 20 and 40 and the shortest RR interval between beats 5 and 25 after standing up in the HRV test.

  • Level of significance: nsP > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001.