Table 1

Incidence of T1D in NHW youth <20 years of age at diagnosis by year, age category, and sex and mean age at diagnosis, overall, and by sex: the SEARCH for Diabetes in Youth Study, 2002–2009

20022003200420052006200720082009
All youth
n712681672710727768792782
 Population (denominator)2,917,5772,892,2752,864,2172,853,3322,855,6362,847,0222,849,5142,847,765
 Age at diagnosis (years)9.68 (4.58)9.44 (4.62)9.83 (4.54)9.90 (4.45)9.95 (4.67)9.99 (4.33)9.80 (4.50)9.88 (4.42)
 Incidence by age category*
  0–4 years20.2 (17.1–23.9)22.5 (19.2–26.4)18.5 (15.5–22.1)17.6 (14.7–21.1)20.1 (17.0–23.8)16.9 (14.0–20.3)19.8 (16.7–23.5)18.5 (15.5–22.0)
  5–9 years31.5 (27.6–35.9)27.5 (23.8–31.7)31.3 (27.4–35.8)33.2 (29.1–37.8)31.7 (27.7–36.2)37.8 (33.5–42.8)37.9 (33.5–42.7)38.7 (34.3–43.6)
  10–14 years31.5 (27.8–35.7)33.4 (29.5–37.7)31.7 (28.0–36.0)37.8 (33.6–42.5)35.6 (31.6–40.2)39.7 (35.4–44.5)39.9 (35.5–44.8)38.5 (34.2–43.3)
  15–19 years14.2 (11.8–17.2)10.9 (8.8–13.5)12.5 (10.2–15.3)11.2 (9.1–13.8)14.8 (12.3–17.7)14.1 (11.7–17.0)14.4 (12.0–17.4)14.8 (12.3–17.8)
 Total24.4 (22.7–26.3)23.5 (21.8–25.4)23.5 (21.7–25.3)24.9 (23.1–26.8)25.4 (23.7–27.4)27.0 (25.1–28.9)27.8 (25.9–29.8)27.5 (25.6–29.4)
 Total, age-adjusted24.4 (23.9–24.8)23.5 (23.1–23.9)23.4 (23.0–23.8)24.8 (24.4–25.3)25.4 (24.9–25.8)26.9 (26.4–27.4)27.7 (27.2–28.2)27.4 (26.9–27.9)
 Total, sex-adjusted24.4 (24.0–24.8)23.5 (23.1–24.0)23.5 (23.0–23.9)24.9 (24.4–25.3)25.4 (25.0–25.9)27.0 (26.5–27.4)27.8 (27.3–28.3)27.5 (27.0–27.9)
 Total, age- and sex-adjusted24.4 (23.9–24.8)23.5 (23.1–23.9)23.4 (23.0–23.8)24.8 (24.4–25.3)25.4 (25.0–25.9)26.9 (26.4–27.4)27.7 (27.3–28.2)27.4 (26.9–27.9)
Females
 n324336324307322362365370
 Age at diagnosis (years)9.19 (4.62)8.95 (4.41)9.72 (4.18)9.48 (4.30)9.60 (4.57)9.58 (4.30)9.45 (4.39)9.69 (4.12)
 Incidence by age category
  0–4 years22.1 (17.6–27.8)23.6 (18.9–29.5)17.2 (13.3–22.4)16.8 (12.9–21.9)21.0 (16.6–26.6)17.4 (13.4–22.6)17.7 (13.7–22.9)15.8 (12–20.7)
  5–9 years30.9 (25.5–37.3)33.6 (27.9–40.4)32.9 (27.3–39.7)32.4 (26.8–39.1)28.8 (23.6–35.2)39.3 (33.1–46.6)41.8 (35.4–49.3)43.1 (36.7–50.7)
  10–14 years26.8 (22.1–32.5)29.3 (24.3–35.3)33.3 (27.9–39.8)32.2 (26.9–38.6)32.1 (26.7–38.5)36.7 (30.9–43.6)34.5 (28.9–41.3)37.6 (31.7–44.6)
  15–19 years11.8 (8.8–15.9)9.9 (7.1–13.6)9.7 (7.0–13.4)7.9 (5.5–11.2)11.4 (8.5–15.4)11.9 (8.9–15.9)12.3 (9.2–16.3)11.0 (8.1–15.0)
 Total22.8 (20.5–25.4)23.9 (21.5–26.6)23.2 (20.8–25.9)22.1 (19.8–24.7)23.1 (20.7–25.8)26.1 (23.5–28.9)26.3 (23.7–29.1)26.7 (24.1–29.5)
 Total, age-adjusted22.8 (22.2–23.4)23.8 (23.2–24.5)23.2 (22.6–23.8)22.1 (21.5–22.7)23.1 (22.5–23.7)26.0 (25.3–26.7)26.2 (25.6–26.9)26.6 (25.9–27.3)
Males
 n388345348402405406426412
 Age at diagnosis (years)10.09 (4.51)9.93 (4.78)9.93 (4.84)10.22 (4.55)10.23 (4.73)10.35 (4.33)10.11 (4.57)10.04 (4.67)
 Incidence by age category
  0–4 years18.4 (14.4–23.6)21.5 (17.1–27.0)19.7 (15.5–25.0)18.4 (14.4–23.6)19.3 (15.1–24.5)16.4 (12.6–21.3)21.8 (17.4–27.3)21.0 (16.7–26.5)
  5–9 years32.1 (26.8–38.5)21.7 (17.4–27.1)29.7 (24.6–36.0)34.0 (28.4–40.7)34.4 (28.8–41.1)36.5 (30.7–43.4)34.2 (28.6–40.8)34.4 (28.9–41.1)
  10–14 years35.9 (30.5–42.3)37.3 (31.7–43.8)30.2 (25.2–36.1)43.1 (37.0–50.2)39.0 (33.2–45.8)42.5 (36.4–49.6)44.9 (38.6–52.3)39.3 (33.4–46.3)
  15–19 years16.5 (12.9–21.1)11.9 (8.9–15.8)15.2 (11.8–19.6)14.4 (11.1–18.7)18.0 (14.3–22.7)16.2 (12.7–20.7)16.5 (13.0–21.0)18.4 (14.6–23.2)
 Total25.9 (23.5–28.6)23.2 (20.9–25.8)23.7 (21.3–26.3)27.5 (24.9–30.3)27.6 (25.1–30.5)27.8 (25.2–30.7)29.2 (26.6–32.1)28.2 (25.6–31.1)
 Total, age-adjusted25.9 (25.3–26.5)23.2 (22.6–23.8)23.6 (23.0–24.2)27.4 (26.8–28.1)27.6 (27.0–28.3)27.8 (27.1–28.4)29.2 (28.5–29.8)28.2 (27.5–28.9)
  • Data are incidence per 100,000 person-years (95% CI) or mean (SD) unless otherwise indicated. All age- and sex-adjusted rates were calculated by using direct adjustment, with the estimated 2002–2009 U.S. intercensal population as the standard population.

  • *Age at diagnosis.