Table 2

Characteristics of T1D participants with DQB1*06:02 by autoantibody status

DQB1*06:02+ (n = 50)*Ab+ (n = 33)Ab (n = 16)P value
HbA1c at diagnosis, % [mmol/mol] (mean ± SD)10.8 ± 2.8 [95 ± 7] (n = 42)11.3 ± 2.9 [100 ± 8] (n = 28)10.0 ± 2.6 [86 ± 5] (n = 14)0.170
DKA at diagnosis (%)0.090
 Yes36 (n = 18)45 (n = 15)19 (n = 3)
 No44 (n = 22)36 (n = 12)63 (n = 10)
 Unknown20 (n = 10)18 (n = 6)19 (n = 3)
HLA-DQ status (%)0.006
DQB1*03:0230 (n = 15)42 (n = 14)0 (n = 0)0.002
DQB1*02:0122 (n = 11)24 (n = 8)19 (n = 3)1.00
 Other48 (n = 24)33 (n = 11)81 (n = 13)0.002
  • * Islet autoantibodies were measured in 49/50 0602+ individuals with T1D.