PET/CT parameters across 4 months of acclimation
| Month 1: 24°C | Month 2: 19°C | Month 3: 24°C | Month 4: 27°C | Ptrend | |
|---|---|---|---|---|---|
| BAT volume (mL) | 55 ± 61 | 78 ± 84a | 63 ± 81 | 58 ± 81 | 0.036 |
| BAT mean SUV | 3.2 ± 0.8 | 3.8 ± 1.3 | 3.4 ± 1.0 | 3.4 ± 0.8 | 0.35 |
| BAT activity (MBq) | 0.65 ± 0.76 | 1.0 ± 1.3a | 0.8 ± 1.1 | 0.7 ± 1.0 | 0.038 |
| BAT radiodensity (HU) | −58.8 ± 7.2 | −44.2 ± 6.8 | −55.4 ± 6.5 | −69.2 ± 6.8 | <0.01 |
| Whole fat mean SUV | 0.61 ± 0.13 | 0.68 ± 0.18a | 0.63 ± 0.17 | 0.59 ± 0.16 | 0.035 |
| Muscle mean SUV | 0.46 ± 0.08 | 0.41 ± 0.04 | 0.43 ± 0.05 | 0.48 ± 0.08 | 0.52 |
| Liver mean SUV | 1.68 ± 0.08 | 1.50 ± 0.14 | 1.61 ± 0.15 | 1.67 ± 0.16 | 0.15 |
Data are means ± SD. At the end of each testing month, subjects underwent acute thermometabolic evaluation at either 24°C or 19°C.
aP < 0.05 (month 1 vs. 2).