Table 3

Association of rs679482 with 26-week PWL in discovery, replication, and combined meta-analysis

StudyNA1A2Freqβ (95% CI)SEPVp§
Discovery521AC0.12−0.38 (−0.56, −0.20)0.093.7E-053.0
Replication1,331AC0.11−0.34 (−0.46, −0.22)0.061.2E-082.3
Meta-analysis1,852AC0.12−0.35 (−0.45, −0.25)0.051.7E-122.6
  • Freq, frequency of A1 allele.

  • 95% CI around regression coefficient, β.

  • § Percentage of phenotypic variance explained by rs679482.