Incidence of T1D in NHW youth <15 years of age at diagnosis by year and sex: the SEARCH for Diabetes in Youth Study, 2002–2009
2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | |
---|---|---|---|---|---|---|---|---|
n | 604 | 598 | 577 | 624 | 612 | 659 | 680 | 668 |
Population (denominator) | 2,159,677 | 2,131,682 | 2,104,425 | 2,086,173 | 2,082,434 | 2,074,901 | 2,077,805 | 2,081,993 |
Total | ||||||||
Unadjusted | 28.0 (25.8–30.3) | 28.1 (25.9–30.4) | 27.4 (25.3–29.7) | 29.9 (27.6–32.3) | 29.4 (27.2–31.8) | 31.8 (29.4–34.3) | 32.7 (30.4–35.3) | 32.1 (29.8–34.6) |
Age-adjusted | 28.0 (27.4–28.5) | 28.1 (27.5–28.6) | 27.4 (26.9–28.0) | 29.9 (29.3–30.5) | 29.4 (28.9–30.0) | 31.8 (31.2–32.4) | 32.8 (32.2–33.4) | 32.2 (31.6–32.8) |
Sex-adjusted | 28.0 (27.4–28.5) | 28.1 (27.5–28.6) | 27.4 (26.9–27.9) | 29.9 (29.3–30.5) | 29.4 (28.8–30.0) | 31.8 (31.2–32.4) | 32.7 (32.1–33.4) | 32.1 (31.5–32.7) |
Age- and sex-adjusted | 28.0 (27.4–28.5) | 28.1 (27.5–28.6) | 27.4 (26.9–28.0) | 29.9 (29.3–30.5) | 29.4 (28.9–30.0) | 31.8 (31.2–32.4) | 32.8 (32.2–33.4) | 32.2 (31.6–32.8) |
Females | ||||||||
n | 280 | 299 | 288 | 278 | 279 | 317 | 319 | 329 |
Unadjusted | 26.7 (23.7–30.0) | 28.9 (25.8–32.3) | 28.1 (25.0–31.6) | 27.4 (24.3–30.8) | 27.5 (24.4–30.9) | 31.4 (28.1–35.0) | 31.5 (28.2–35.2) | 32.4 (29.1–36.1) |
Age-adjusted | 26.7 (25.9–27.4) | 28.9 (28.1–29.7) | 28.1 (27.3–28.9) | 27.4 (26.6–28.2) | 27.5 (26.7–28.3) | 31.4 (30.5–32.2) | 31.5 (30.7–32.4) | 32.5 (31.6–33.4) |
Males | ||||||||
n | 324 | 299 | 289 | 346 | 333 | 342 | 361 | 339 |
Unadjusted | 29.2 (26.2–32.6) | 27.3 (24.4–30.6) | 26.7 (23.8–30.0) | 32.3 (29.1–35.9) | 31.2 (28.0–34.8) | 32.1 (28.9–35.7) | 33.9 (30.6–37.6) | 31.8 (28.6–35.4) |
Age-adjusted | 29.2 (28.5–30.0) | 27.3 (26.5–28.0) | 26.7 (26–27.5) | 32.3 (31.5–33.1) | 31.2 (30.4–32.1) | 32.2 (31.4–33.0) | 34.0 (33.1–34.9) | 31.9 (31.1–32.7) |
Data are incidence per 100,000 person-years (95% CI) unless otherwise indicated. All age- and sex-adjusted rates were calculated by using direct adjustment with the estimated 2002–2009 U.S. intercensal population as the standard population.