Table 1

Plasma parameters of DIO FGF21 tissue-specific knockout mice

DIO FGF21fl/flDIO FGF21 LivKODIO FGF21fl/flDIO FGF21 AdipoKO
n8988
Food intake (g/day)2.61 ± 0.082.60 ± 0.072.65 ± 0.062.68 ± 0.10
Triglycerides (mg/dL)65.70 ± 3.7562.73 ± 2.7074.80 ± 4.6482.58 ± 5.89
NEFAs (mmol/L)0.49 ± 0.030.50 ± 0.030.58 ± 0.040.53 ± 0.03
β-Hydroxybutyrate (µmol/L)54.86 ± 9.8760.78 ± 6.6756.67 ± 7.1143.84 ± 5.09
Glucagon (pg/mL)85.99 ± 20.2677.95 ± 26.8450.78 ± 4.1065.24 ± 8.56
Adiponectin (ng/mL)15.07 ± 0.4414.57 ± 0.1715.03 ± 0.5115.27 ± 0.50
  • Data are mean ± SEM unless otherwise indicated. Plasma parameters were measured in DIO FGF21 LivKO, FGF21 AdipoKO, and FGF21fl/fl littermate controls.