Table 1

Subject characteristics

CD36-deficient: homozygous family membersCD36-sufficientP
Heterozygous family members Control subjects
n235
Sex (male/female)1/11/22/3
Age (years)25/2241 ± 2034 ± 16
BMI (kg/m2)22.6/21.421.8 ± 1.222.3 ± 1.8
Body fat (%)19/2428 ± 624 ± 6
Abdominal subcutaneous adipose tissue
 Adipocyte size (µg/cell)0.59/0.920.79 ± 0.210.29 ± 0.090.003
 CD36 (arbitrary units/mg tissue)6.3 ± 4.510.6 ± 2.90.23
 ACS (pmol/min/mg tissue)64/5761 ± 2271 ± 200.40
 DGAT (pmol/min/mg tissue)5.8/10.98.6 ± 2.87.3 ± 1.5 (n = 4)0.41
Thigh subcutaneous adipose tissue
 Adipocyte size (µg lipid/cell)0.36/0.780.73 ± 0.320.72 ± 0.330.80
 CD36 (arbitrary units/mg tissue)4.9 ± 2.211.5 ± 4.70.04
 ACS (pmol/min/mg tissue)61/5656 ± 2087 ± 240.05
 DGAT (pmol/min/mg tissue)4.5/10.99.8 ± 4.38.7 ± 2.40.92
  • The normally distributed data, presented as means ± SD, are from family members (n = 5) and control subjects (n = 5) unless otherwise noted. The individual data for the two homozygous Pro90Ser family members are provided. Age, BMI, and body fat were intentionally matched and thus not subject to statistical testing.