Table 1

Baseline participant characteristics stratified by study

T1D (n = 50)Control (n = 20)P value
Age (years)16.0 ± 3.016.1 ± 2.90.94
Tanner stage5 (4–5)5 (4–5)0.99
T1D duration (years)5.7 ± 2.6
Sex, female (%)50%70%0.13
Race/ethnicity (%)
 Black non-Hispanic250.41
 Hispanic60
 White non-Hispanic9295
 Other00
BMI (kg/m2)23.4 ± 5.122.7 ± 3.70.58
Weight (kg)67.5 ± 17.662.7 ± 14.50.28
Fat mass (kg)20.3 ± 9.419.2 ± 6.70.62
Blood pressure (mmHg)
 Systolic blood pressure119 ± 9117 ± 80.30
 Diastolic blood pressure74 ± 1173 ± 110.89
 MAP89 ± 988 ± 90.66
UACR (mg/g)6 (5–14)7 (4–10)0.87
GFR (mL/min)189 ± 40136 ± 22<0.0001
GFR (mL/min/1.73 m2)183 ± 26139 ± 8<0.0001
RPF (mL/min)820 ± 125615 ± 65<0.0001
RPF (mL/min/1.73 m2)824 ± 120634 ± 85<0.0001
Hematocrit (%)41.7 ± 2.841.8 ± 2.90.95
Lactate (mg/dL)32.5 ± 7.227.9 ± 8.10.03
KIM-1 (pg/mL)27.1 ± 12.428.4 ± 9.40.67
HbA1c (%)8.7 ± 1.35.2 ± 0.2<0.0001
LDL cholesterol (mg/dL)89 ± 2492 ± 240.65
HDL cholesterol (mg/dL)51 ± 1046 ± 90.08
Triglycerides (mg/dL)78 ± 3588 ± 360.27
eIS7.2 ± 2.19.9 ± 2.0<0.0001
GIR at steady state (M) (mg/kg/min)3.7 ± 1.9
Insulin at steady state (μIU/mL)33 ± 18
M/I (mg/kg/min per μIU/mL insulin × 100)10.9 (6.9–16.6)
M/I (mg/lean kg/min per μIU/mL insulin × 100)15.7 (11.1–26.2)
  • Data are presented as mean ± SD or median (IQR), unless otherwise noted.