Table 4

Associations between genetically predicted PCOS and risk of type 2 diabetes, CHD, and stroke with use of the IVW method

TraitIVWCochran Q statistic
OR (95% CI)PTest statisticP
Diabetes in Asian (all)0.98 (0.96–1.01)0.1323.480.02
 Female0.98 (0.95–1.02)0.3311.400.50
 Male0.99 (0.95–1.02)0.4514.450.27
Diabetes in European (all)0.97 (0.92–1.01)0.1629.790.005
 Female0.95 (0.88–1.02)0.1629.380.006
 Male0.98 (0.93–1.03)0.4215.660.27
CHD1.00 (0.96–1.04)0.8824.420.03
 Any stroke0.98 (0.93–1.02)0.3310.210.68
  Any ischemic stroke0.98 (0.93–1.03)0.408.260.83
   Large artery stroke0.88 (0.78–1.00)0.0612.160.51
   Cardioembolic stroke0.92 (0.83–1.02)0.1013.880.38
   Small vessel stroke1.10 (0.95–1.27)0.2118.590.14