Table 2

PCOS SNPs used to construct the main instrument variable in East Asians

Chr:positionSNPEffect alleleOther alleleEAFβSENearest genePF statistic
2:43638838rs13429458AC0.810.4010.040THADA1.73E−2399.75
2:48978159rs13405728AG0.7540.3430.037LHCGR7.55E−2187.72
2:49201612rs2268361CT0.5040.1390.020FSHR9.89E−1350.87
2:49247832rs2349415TC0.1810.1740.025FSHR2.35E−1249.17
9:97648587rs4385527GA0.7810.1740.030C9orf35.87E−0933.88
9:97741336rs3802457GA0.9040.2610.035C9orf35.28E−1456.62
9:126525212rs2479106GA0.2220.2930.033DENND1A8.12E−1978.47
11:102070639rs1894116GA0.1940.2390.024YAP11.08E−2296.12
12:56390636rs705702GA0.2450.2390.023RAB5B/SUOX8.64E−26110.25
12:66224461rs2272046AC0.9070.3570.038HMGA21.95E−2190.4
16:52347819rs4784165GT0.3250.1400.021TOX33.64E−1143.8
19:7166109rs2059807GA0.3010.1310.023INSR1.09E−0832.67
20:52447303rs6022786AG0.3390.1220.020SUMO1P11.83E−0936.15
  • Chr, chromosome; EAF, effect allele frequency.