Table 2

PCOS SNPs used to construct the main instrument variable in East Asians

Chr:position	SNP	Effect allele	Other allele	EAF	β	SE	Nearest gene	P	F statistic
2:43638838	rs13429458	A	C	0.81	0.401	0.040	THADA	1.73E−23	99.75
2:48978159	rs13405728	A	G	0.754	0.343	0.037	LHCGR	7.55E−21	87.72
2:49201612	rs2268361	C	T	0.504	0.139	0.020	FSHR	9.89E−13	50.87
2:49247832	rs2349415	T	C	0.181	0.174	0.025	FSHR	2.35E−12	49.17
9:97648587	rs4385527	G	A	0.781	0.174	0.030	C9orf3	5.87E−09	33.88
9:97741336	rs3802457	G	A	0.904	0.261	0.035	C9orf3	5.28E−14	56.62
9:126525212	rs2479106	G	A	0.222	0.293	0.033	DENND1A	8.12E−19	78.47
11:102070639	rs1894116	G	A	0.194	0.239	0.024	YAP1	1.08E−22	96.12
12:56390636	rs705702	G	A	0.245	0.239	0.023	RAB5B/SUOX	8.64E−26	110.25
12:66224461	rs2272046	A	C	0.907	0.357	0.038	HMGA2	1.95E−21	90.4
16:52347819	rs4784165	G	T	0.325	0.140	0.021	TOX3	3.64E−11	43.8
19:7166109	rs2059807	G	A	0.301	0.131	0.023	INSR	1.09E−08	32.67
20:52447303	rs6022786	A	G	0.339	0.122	0.020	SUMO1P1	1.83E−09	36.15